刘朋朋课题组

  • 刘朋朋
  • 助理教授 博士生导师
  • 电子邮箱: liupengpenggene@126.com

Education

Ph.D., (Cell Biology), Peking University, Beijing, China
Thesis Title: Application of CRISPR/Cas9 system for genome editing in C.elegans
Advisor: Zuoyan Zhu, PhD

7/2014

B.S., Biotechnology, ZhengZhou University, HeNan, China

7/2008

Postdoctoral Training


Postdoctoral Associate
Department of Molecular, Cell and Cancer Biology. University of Massachusetts Chan Medical School, Worcester, MASupervisor: Scot Wolfe, PhD

 

7/2015 – 4/2022

Academic Appointments

Instructor

Department of Molecular, Cell and Cancer Biology. University of Massachusetts                                                 

 

 

5/2022 ~  10/2024                                                                                                                                     




Patents

Enhanced bcl11a rnp/crispr delivery & editing using a 3xnls-cas9 (PCT/WIPO)

(https://patents.google.com/patent/WO2019213273A1/en)

 

Targeting bcl11a distal regulatory elements with a cas9-cas9 fusion for fetal hemoglobin re-induction. (PCT/WIPO)

(https://patents.google.com/patent/WO2019147302A1/en)

 

Programmable dna base editing by nme2cas9-deaminase fusion proteins ((PCT/WIPO))

(https://patents.google.com/patent/WO2020081568A1/)

 

Improved cas12a/nls mediated therapeutic gene editing platforms (PCT/WIPO)

(https://patents.google.com/patent/WO2021216674A1/en)

 

A cas9-pdbd base editor platform with improved targeting range and specificity (US Patent)

(https://www.freepatentsonline.com/y2023/0049455.html)

 

Prime editor system for in vivo genome editing (US Patent)

(https://patents.google.com/patent/US20230374476A1/en)

 

 

Improved Prime Editor for Genome Editing via Chemical modifications of PegRNA (PCT/WIPO, pending)